Rabbit Polyclonal Antibody to S10A1
货号:
P41834
别名:
S100-ALPHA ; S100 CALCIUM-BINDING PROTEIN A1;
应用:
WB,IHC,IF
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P23297
规格:
目录价
在线咨询
Description |
---|
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.Patrick Most, J. Biol. Chem., Nov 2003; 278: 48404 - 48412. Miki Okada, J. Biol. Chem., Feb 2004; 279: 4221 - 4233. Melanie Boerries, Mol. Cell. Biol., Jun 2007; 27: 4365 - 4373. Patrick Most, J. Clin. Invest., Dec 2004; 114: 1550 - 1563. |
Specification |
|
---|---|
Aliases | S100-ALPHA ; S100 CALCIUM-BINDING PROTEIN A1; |
Entrez GeneID | 6271; |
Swissprot | P23297 |
WB Predicted band size | 10kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from human S100 A1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
IF | 1/100-1/500 |
Product Image
-
Western blot analysis of extracts from A549 cells, using S100 A1 antibody P41834.
-
Western blot analysis of extracts from 293 cells (Lane 2), using S100 A1 antiobdy P41834. The lane on the left is treated with synthesized peptide.
-
Immunofluorescence analysis of A549 cells, using S100 A1 antibody P41834.
-
Immunohistochemical analysis of paraffin-embedded human brain tissue using S100 A1 antibody P41834.