Rabbit Polyclonal Antibody to RIT1
货号：
P41833
别名：
GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q92963
规格：
目录价
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Description |
|---|
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 - 8197. Angus Chen, J. Biol. Chem., May 2000; 275: 15432. Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 - 1393. Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 - 527. |
Specification |
|
|---|---|
| Aliases | GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT |
| Entrez GeneID | 6016; |
| Swissprot | Q92963 |
| WB Predicted band size | 25kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from human RIT1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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