Rabbit Polyclonal Antibody to RCC1
货号：
P41830
别名：
CHC1; Cell cycle regulatory protein; Regulator of chromosome condensation;
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P18754
规格：
目录价
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Description |
|---|
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.M Dasso, Mol. Cell. Biol., Aug 1992; 12: 3337 - 3345. Hoi Yeung Li, J. Cell Biol., Mar 2003; 160: 635. Michael E. Nemergut, Science, May 2001; 292: 1540. Ian Cushman, Mol. Biol. Cell, Jan 2004; 15: 245. |
Specification |
|
|---|---|
| Aliases | CHC1; Cell cycle regulatory protein; Regulator of chromosome condensation; |
| Entrez GeneID | 1104;; |
| Swissprot | P18754 |
| WB Predicted band size | 58kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from human RCC1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from LOVO cells, using RCC1 antibody P41830.
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Western blot analysis of extracts from HepG2 cells (Lane 2), cells (Lane 3) and cells (Lane 4), using RCC1 antiobdy P41830. The lane on the left is treated with systhesized peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RCC1 antibody P41830.
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