Rabbit Polyclonal Antibody to TNF Receptor-1
货号：
P41845
别名：
CD120a; TBPI; TNF-RI; TNFAR; TNFR1
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P19438
规格：
目录价
在线咨询
Description |
|---|
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase |
References |
|---|
| Jennifer Adjodha, AACR Meeting Abstracts, Apr 2006; 2006: 1028. Kewu Huang, J Appl Physiol, Apr 2007; 102: 1632 - 1639. Kiyoshi Asada, AACR Meeting Abstracts, Apr 2005; 2005: 202. Elaine K Green, J. Med. Genet., Aug 2000; 37: 581. |
Specification |
|
|---|---|
| Aliases | CD120a; TBPI; TNF-RI; TNFAR; TNFR1 |
| Entrez GeneID | 7132; |
| Swissprot | P19438 |
| WB Predicted band size | 50kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from Internal of human TNF receptor-1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-2000 |
| IHC | 1/50-1/200 |
| IF | 1/100-1/500 |
鄂公网安备42018502007531号
