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Mouse Monoclonal Antibody to FGF2
货号: 31792
别名: BFGF; FGFB; FGF-2; HBGF-2
应用: IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: P09038
规格:
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Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

References

1.Stem Cell Reports. 2018 Aug 14;11(2):325-333.
2. Immunol. 2017 Nov 1;199(9):3086-3093.

Specification

Aliases BFGF; FGFB; FGF-2; HBGF-2
Entrez GeneID 2247
Swissprot P09038
clone 1D6B5
WB Predicted band size 30.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human FGF2 (AA: 143-288) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/200 - 1/1000
ELISA 1/10000
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