Rabbit Polyclonal Antibody to Cyclin-L1
货号：
P41827
别名：
Cyclin-L; CCNL1;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9UK58
规格：
目录价
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Description |
|---|
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.A. Hamid Boulares, J. Biol. Chem., Aug 1999; 274: 22932. Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007; 10.1152.Mi Young Kim, Genes & Dev., Sep 2005; 19: 1951 - 1967. Silke S篓鹿sse, Nucleic Acids Res., Feb 2004; 32: 669 - 680. |
Specification |
|
|---|---|
| Aliases | Cyclin-L; CCNL1; |
| Entrez GeneID | 57018; |
| Swissprot | Q9UK58 |
| WB Predicted band size | 60kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human Cyclin-L1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody P41827.
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Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin-L1 antiobdy P41827. The lane on the left is treated with systhesized peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin-L1 antibody P41827.
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