Rabbit Polyclonal Antibody to CTRO
货号:
P41859
别名:
Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O14578
规格:
目录价
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Description |
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Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.Nagase T., DNA Res. 6:63-70(1999).Scherer S.E., Nature 440:346-351(2006).Gruneberg U., J. Cell Biol. 172:363-372(2006). |
Specification |
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Aliases | Citron Rho-interacting kinase; CRIK; Rho-interacting; serine/threonine-protein kinase 21; CIT |
Entrez GeneID | 11113; |
Swissprot | O14578 |
WB Predicted band size | 231kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human CTRO. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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IHC | 1/50-1/100 |