Rabbit Polyclonal Antibody to 45202
货号:
P41825
别名:
41915; OCT4; OTF3; OTF4; OCTAMER-BINDING TRANSCRIPTION FACTOR 3
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q01860
规格:
目录价
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Description |
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Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency |
References |
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Y Saijoh, Genes Cells, Feb 1996; 1: 239 - 252. Christopher L. Shaffer, Drug Metab. Dispos., Apr 2007; 10.1124 Brian Boer, Nucleic Acids Res., Mar 2007; 35: 1773 - 1786. E Pikarsky, Mol. Cell. Biol., Feb 1994; 14: 1026 - 1038. |
Specification |
|
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Aliases | 41915; OCT4; OTF3; OTF4; OCTAMER-BINDING TRANSCRIPTION FACTOR 3 |
Entrez GeneID | 5460; |
Swissprot | Q01860 |
WB Predicted band size | 50kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from human OCT3 antibody. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HeLa cells, using OCT3 antibody P41825.
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Western blot analysis of extracts from 293 cells (Lane 2), using OCT3 antiobdy P41825. The lane on the left is treated with synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using OCT3 antibody P41825.