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Rabbit Polyclonal Antibody to NKX3.1
货号: P41824
别名: Homeobox protein Nkx-3.1; NKX31; NKX3A;
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q99801
规格:
目录价
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Description

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.Cai Bowen, Cancer Res., Jan 2007; 67: 455 - 464. Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017. Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173. Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690.

Specification

Aliases Homeobox protein Nkx-3.1; NKX31; NKX3A;
Entrez GeneID 4824;
Swissprot Q99801
WB Predicted band size 38kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from N-terminal of human NKX3.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/50-1/100
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