Rabbit Polyclonal Antibody to NKX3.1
货号:
P41824
别名:
Homeobox protein Nkx-3.1; NKX31; NKX3A;
应用:
IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q99801
规格:
目录价
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Description |
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Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.Cai Bowen, Cancer Res., Jan 2007; 67: 455 - 464. Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017. Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173. Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690. |
Specification |
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Aliases | Homeobox protein Nkx-3.1; NKX31; NKX3A; |
Entrez GeneID | 4824; |
Swissprot | Q99801 |
WB Predicted band size | 38kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from N-terminal of human NKX3. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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IHC | 1/50-1/100 |