Rabbit Polyclonal Antibody to XPA
货号：
P41849
别名：
DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein;
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P23025
规格：
目录价
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Description |
|---|
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.Gary W. Daughdrill, Nucleic Acids Res., Jul 2003; 31: 4176 - 4183. Esther M. Hoogervorst, Carcinogenesis, Mar 2003; 24: 613 - 619. Karen M. Vasquez, PNAS, Apr 2002; 99: 5848. |
Specification |
|
|---|---|
| Aliases | DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein; |
| Entrez GeneID | 7507; |
| Swissprot | P23025 |
| WB Predicted band size | 40kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from Internal of human XPA. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from COLO205 cells, using XPA antibody P41849.
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Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy P41849. The lane on the left is treated with systhesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XPA antibody P41849.
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