Rabbit Polyclonal Antibody to SIN3B
货号：
P41878
别名：
Paired amphipathic helix protein Sin3b; Transcriptional corepressor Sin3b; Histone deacetylase complex subunit Sin3b; SIN3B; KIAA0700
应用：
WB,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O75182
规格：
目录价
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Description |
|---|
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription By similarity.Ishikawa K., DNA Res. 5:169-176(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Wysocka J., Genes Dev. 17:896-911(2003). |
Specification |
|
|---|---|
| Aliases | Paired amphipathic helix protein Sin3b; Transcriptional corepressor Sin3b; Histone deacetylase complex subunit Sin3b; SIN3B; KIAA0700 |
| Entrez GeneID | 23309; |
| Swissprot | O75182 |
| WB Predicted band size | 130kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human SIN3B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IF | 1/100-1/500 |
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