Rabbit Polyclonal Antibody to ZIC1/2/3
货号：
P41873
别名：
Zinc finger protein ZIC 1; Zinc finger protein of the cerebellum 1; ZIC1;
应用：
WB,IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q15915
规格：
目录价
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Description |
|---|
Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' By similarity.Yokota N., Cancer Res. 56:377-383(1996). |
Specification |
|
|---|---|
| Aliases | Zinc finger protein ZIC 1; Zinc finger protein of the cerebellum 1; ZIC1; |
| Entrez GeneID | 7545; |
| Swissprot | Q15915 |
| WB Predicted band size | 51kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human ZIC1/2/3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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