Rabbit Polyclonal Antibody to TFIP8
货号:
P41890
别名:
Tumor necrosis factor; alpha-induced protein 8; Head and neck tumor and metastasis-related protein; TNF-induced protein GG2-1; SCC-S2
应用:
WB,IHC,IF
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
O95379
规格:
目录价
在线咨询
Description |
---|
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.Horrevoets A.J.G., Blood 93:3418-3431(1999).Kumar D., J. Biol. Chem. 275:2973-2978(2000).You Z., J. Biol. Chem. 276:26398-26404(2001). |
Specification |
|
---|---|
Aliases | Tumor necrosis factor; alpha-induced protein 8; Head and neck tumor and metastasis-related protein; TNF-induced protein GG2-1; SCC-S2 |
Entrez GeneID | 25816; |
Swissprot | O95379 |
WB Predicted band size | 23kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from internal of human TFIP8. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
IF | 1/100-1/500 |