Rabbit Polyclonal Antibody to FIR
货号：
P41887
别名：
FERM; RhoGEF and pleckstrin domain protein 2; FGD1-related Cdc42-GEF; FIR; FRG
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
O94887
规格：
目录价
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Description |
|---|
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity.Nagase T., DNA Res. 5:31-39(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Jandrig B., Oncogene 23:9295-9302(2004). |
Specification |
|
|---|---|
| Aliases | FERM; RhoGEF and pleckstrin domain protein 2; FGD1-related Cdc42-GEF; FIR; FRG |
| Entrez GeneID | 9855; |
| Swissprot | O94887 |
| WB Predicted band size | 119kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from Internal of human FIR. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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