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Rabbit Polyclonal Antibody to Heparin Cofactor II
货号: P41900
别名: Heparin cofactor 2 [Precursor]; Heparin cofactor II; HC-II; Protease inhibitor leuserpin 2; HLS2
应用: WB,IHC,IF
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P05546
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Description

Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.Blinder M.A., Biochemistry 27:752-759(1988).Herzog R., Biochemistry 30:1350-1357(1991).Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Specification

Aliases Heparin cofactor 2 [Precursor]; Heparin cofactor II; HC-II; Protease inhibitor leuserpin 2; HLS2
Entrez GeneID 3053;
Swissprot P05546
WB Predicted band size 57kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from internal of human Heparin Cofactor II.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
IF 1/100-1/200
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