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Rabbit Polyclonal Antibody to Adrenergic Receptor alpha-2B
货号: P41918
别名: ADA2B; ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR
应用: IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: P18089
规格:
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Description

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).Small K.M., J. Biol. Chem. 276:4917-4922(2001).

Specification

Aliases ADA2B; ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR
Entrez GeneID 151;
Swissprot P18089
WB Predicted band size 50kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IF 1/100-1/500
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