Mouse Monoclonal Antibody to HER-2
货号：
20127
别名：
HER-2, C-erB-2, erbB-2
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P04626
规格：
目录价
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Description |
|---|
The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis |
References |
|---|
| 1. RR Mehta, JH McDermott, TJ Hieken, et al. J. Clin. Oncol. 1998;16:2409 - 2416. 2. Hideko Y, Vered S, and Daniel F.H, et al. J. Clin. Oncol.2001;19:2334 - 2356. 3. Magali F, Kamel H, C |
Specification |
|
|---|---|
| Aliases | HER-2, C-erB-2, erbB-2 |
| Entrez GeneID | 2064 |
| Swissprot | P04626 |
| clone | 9B9D8 |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of HER-2 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
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