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Rabbit Polyclonal Antibody to MEKKK 4
货号: P41895
别名: EC 2.7.11.1; HPK/GCK-like kinase HGK; M4K4; MAP4K4; MAPK/ERK kinase kinase kinase 4
应用: WB,IF
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: O95819
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Description

Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.Yao Z., J. Biol. Chem. 274:2118-2125(1999).Wright J.H., Mol. Cell. Biol. 23:2068-2082(2003).Ishikawa K., DNA Res. 5:169-176(1998).

Specification

Aliases EC 2.7.11.1; HPK/GCK-like kinase HGK; M4K4; MAP4K4; MAPK/ERK kinase kinase kinase 4
Entrez GeneID 9448;
Swissprot O95819
WB Predicted band size 142kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human MEKKK 4.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IF 1/100-1/500
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