Rabbit Polyclonal Antibody to IRF2
货号：
P41910
别名：
IRF2; Interferon regulatory factor 2;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P14316
规格：
目录价
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Description |
|---|
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.Itoh S., Nucleic Acids Res. 17:8372-8372(1989).Cha Y., J. Biol. Chem. 269:5279-5287(1994).Staal A., J. Cell. Physiol. 185:269-279(2000). |
Specification |
|
|---|---|
| Aliases | IRF2; Interferon regulatory factor 2; |
| Entrez GeneID | 3660; |
| Swissprot | P14316 |
| WB Predicted band size | 47kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from internal of human IRF2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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