Rabbit Polyclonal Antibody to Hexokinase-3
货号：
P41965
别名：
Hexokinase-3; EC 2.7.1.1; Hexokinase type III; HK III; HK3
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P52790
规格：
目录价
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Description |
|---|
Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).Furuta H., Genomics 36:206-209(1996).Palma F., Mol. Cell. Biochem. 155:23-29(1996).Sjoeblom T., Science 314:268-274(2006). |
Specification |
|
|---|---|
| Aliases | Hexokinase-3; EC 2.7.1.1; Hexokinase type III; HK III; HK3 |
| Entrez GeneID | 3101; |
| Swissprot | P52790 |
| WB Predicted band size | 99kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human Hexokinase-3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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