Rabbit Polyclonal Antibody to ST5
货号：
P41979
别名：
Suppression of tumorigenicity 5; HeLa tumor suppression 1; DENN domain-containing protein 2B; ST5; DENND2B
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P78524
规格：
目录价
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Description |
|---|
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996).Amid C., Cytogenet. Cell Genet. 93:284-290(2001).Lichy J.H., Cell Growth Differ. 3:541-548(1992). |
Specification |
|
|---|---|
| Aliases | Suppression of tumorigenicity 5; HeLa tumor suppression 1; DENN domain-containing protein 2B; ST5; DENND2B |
| Entrez GeneID | 6764; |
| Swissprot | P78524 |
| WB Predicted band size | 126kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human ST5. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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