Rabbit Polyclonal Antibody to MAT1
货号:
P41961
别名:
AMS1; AdoMet synthetase; EC 2.5.1.6; MAT-I/III; MATA1
应用:
WB
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P51948
规格:
目录价
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Description |
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Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.Tassan J.-P., EMBO J. 14:5608-5617(1995).Yee A., Cancer Res. 55:6058-6062(1995).Tirode F., Mol. Cell 3:87-95(1999). |
Specification |
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Aliases | AMS1; AdoMet synthetase; EC 2.5.1.6; MAT-I/III; MATA1 |
Entrez GeneID | 4331; |
Swissprot | P51948 |
WB Predicted band size | 36kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from internal of human MAT1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |