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Mouse Monoclonal Antibody to CD163
货号: 31804
别名: M130; MM130; SCARI1
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q86VB7
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Description

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References

1.J Cancer Res Clin Oncol. 2018 Jul;144(7):1253-1263.
2.Cancer Biomark. 2018 Feb 14;21(3):689-700.

Specification

Aliases M130; MM130; SCARI1
Entrez GeneID 9332
Swissprot Q86VB7
clone 8B7D11
WB Predicted band size 125.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD163 (AA: extra 42-259) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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