Mouse Monoclonal Antibody to CD163
货号:
31804
别名:
M130; MM130; SCARI1
应用:
FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q86VB7
规格:
目录价
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Description |
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The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
References |
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1.J Cancer Res Clin Oncol. 2018 Jul;144(7):1253-1263. 2.Cancer Biomark. 2018 Feb 14;21(3):689-700. |
Specification |
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Aliases | M130; MM130; SCARI1 |
Entrez GeneID | 9332 |
Swissprot | Q86VB7 |
clone | 8B7D11 |
WB Predicted band size | 125.4kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD163 (AA: extra 42-259) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |