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Rabbit Polyclonal Antibody to MAEA
货号: P42030
别名: Macrophage erythroblast attacher; Erythroblast macrophage protein; Cell proliferation-inducing gene 5 protein; Lung cancer-related protein 10; HLC-10
应用: WB
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q7L5Y9
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Description

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.Ota T., Nat. Genet. 36:40-45(2004).Hanspal M., Blood 92:2940-2950(1998).Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

Specification

Aliases Macrophage erythroblast attacher; Erythroblast macrophage protein; Cell proliferation-inducing gene 5 protein; Lung cancer-related protein 10; HLC-10
Entrez GeneID 10296;
Swissprot Q7L5Y9
WB Predicted band size 45kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from internal of human MAEA.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
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