Rabbit Polyclonal Antibody to NFIL3
货号：
P42015
别名：
Nuclear factor interleukin-3-regulated protein; E4 promoter binding-protein 4; Interleukin-3 promoter transcriptional activator; Transcriptional activator NF-IL3A; Interleukin-3 binding-protein 1
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q16649
规格：
目录价
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Description |
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Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts By similarity. Represses transcriptional activity of PER1 By similarity. Represses transcriptional activity of PER2 via the B-site on the promoter By similarity. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) By similarity. Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock By similarity. Protects pro-B cells from programmed cell death By similarity.Cowell I.G., Mol. Cell. Biol. 12:3070-3077(1992).Zhang W., Mol. Cell. Biol. 15:6055-6063(1995).Humphray S.J., Nature 429:369-374(2004). |
Specification |
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|---|---|
| Aliases | Nuclear factor interleukin-3-regulated protein; E4 promoter binding-protein 4; Interleukin-3 promoter transcriptional activator; Transcriptional activator NF-IL3A; Interleukin-3 binding-protein 1 |
| Entrez GeneID | 4783; |
| Swissprot | Q16649 |
| WB Predicted band size | 51kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from internal of human NFIL3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
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