Rabbit Polyclonal Antibody to DGKH
货号:
P42035
别名:
iacylglycerol kinase eta; EC 2.7.1.107; Diglyceride kinase eta; DGK-eta; DAG kinase eta
应用:
IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q86XP1
规格:
目录价
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Description |
|---|
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.Murakami T., J. Biol. Chem. 278:34364-34372(2003) .Dunham A., Nature 428:522-528(2004). Ota T., Nat. Genet. 36:40-45(2004). |
Specification |
|
|---|---|
| Aliases | iacylglycerol kinase eta; EC 2.7.1.107; Diglyceride kinase eta; DGK-eta; DAG kinase eta |
| Entrez GeneID | 160851; |
| Swissprot | Q86XP1 |
| WB Predicted band size | 135kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human DGKH. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/50-1/100 |
| IF | 1/100-1/500 |




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