Rabbit Polyclonal Antibody to MKL1
货号:
P42078
别名:
Myocardin-related transcription factor A; MRTF-A; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein;
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q969V6
规格:
目录价
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Description |
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Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.Ma Z., Nat. Genet. 28:220-221(2001).Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).Nagase T., DNA Res. 7:65-73(2000). |
Specification |
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Aliases | Myocardin-related transcription factor A; MRTF-A; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein; |
Entrez GeneID | 57591; |
Swissprot | Q969V6 |
WB Predicted band size | 99kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from N-terminal of human MKL1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |