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Rabbit Polyclonal Antibody to HES6
货号: P42086
别名: Transcription cofactor HES-6; Hairy and enhancer of split 6; C-HAIRY1; HES6;
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q96HZ4
规格:
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Description

Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation By similarity. UniProtKB Q9JHE6Bae S.-K., Development 127:2933-2943(2000).Vasiliauskas D., Mech. Dev. 98:133-137(2000).Ota T., Nat. Genet. 36:40-45(2004).

Specification

Aliases Transcription cofactor HES-6; Hairy and enhancer of split 6; C-HAIRY1; HES6;
Entrez GeneID 55502;
Swissprot Q96HZ4
WB Predicted band size 30kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from N-terminal of human HES6.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
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