Rabbit Polyclonal Antibody to HES6
货号:
P42086
别名:
Transcription cofactor HES-6; Hairy and enhancer of split 6; C-HAIRY1; HES6;
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q96HZ4
规格:
目录价
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Description |
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Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation By similarity. UniProtKB Q9JHE6Bae S.-K., Development 127:2933-2943(2000).Vasiliauskas D., Mech. Dev. 98:133-137(2000).Ota T., Nat. Genet. 36:40-45(2004). |
Specification |
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Aliases | Transcription cofactor HES-6; Hairy and enhancer of split 6; C-HAIRY1; HES6; |
Entrez GeneID | 55502; |
Swissprot | Q96HZ4 |
WB Predicted band size | 30kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from N-terminal of human HES6. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |