Rabbit Polyclonal Antibody to CLK4
货号:
P42111
别名:
Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4;
应用:
WB
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q9HAZ1
规格:
目录价
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Description |
|---|
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.Schultz J., Genomics 71:368-370(2001).McNally T., Protein Sci. 12:1562-1566(2003).Kantham L., Biochem. Biophys. Res. Commun. 304:125-129(2003). |
Specification |
|
|---|---|
| Aliases | Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4; |
| Entrez GeneID | 57396; |
| Swissprot | Q9HAZ1 |
| WB Predicted band size | 65kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human CLK4. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |


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