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Rabbit Polyclonal Antibody to FOXD3
货号: P42136
别名: Forkhead box protein D3; HNF3/FH transcription factor genesis; FOXD3;
应用: WB,IHC
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q9UJU5
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Description

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.Gregory S.G., Nature 441:315-321(2006).Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.

Specification

Aliases Forkhead box protein D3; HNF3/FH transcription factor genesis; FOXD3;
Entrez GeneID 27022;
Swissprot Q9UJU5
WB Predicted band size 48kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human FOXD3.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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