Rabbit Polyclonal Antibody to MLTK
货号：
P42120
别名：
AZK; EC 2.7.11.25; MLTK; MRK-beta; mixed lineage kinase-related kinase
应用：
WB,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9NYL2
规格：
目录价
在线咨询
Description |
|---|
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.Gotoh I., J. Biol. Chem. 276:4276-4286(2001). Bloem L.J., J. Mol. Cell. Cardiol. 33:1739-1750(2001).Gross E.A., J. Biol. Chem. 277:13873-13882(2002). |
Specification |
|
|---|---|
| Aliases | AZK; EC 2.7.11.25; MLTK; MRK-beta; mixed lineage kinase-related kinase |
| Entrez GeneID | 51776; |
| Swissprot | Q9NYL2 |
| WB Predicted band size | 91kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from C-terminal of human MLTK. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IF | 1/100-1/500 |
鄂公网安备42018502007531号
