Rabbit Polyclonal Antibody to CNOT7
货号：
P42134
别名：
BTG1 binding factor 1; BTG1-binding factor 1; CCR4-NOT transcription complex; 7; CCR4-associated factor 1
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UIV1
规格：
目录价
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Description |
|---|
Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.Bogdan J.A., Biochem. J. 336:471-481(1998).The MGC Project Team; Genome Res. 14:2121-2127(2004). |
Specification |
|
|---|---|
| Aliases | BTG1 binding factor 1; BTG1-binding factor 1; CCR4-NOT transcription complex; 7; CCR4-associated factor 1 |
| Entrez GeneID | 29883; |
| Swissprot | Q9UIV1 |
| WB Predicted band size | 36kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from N-terminal of human CNOT7. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
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