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Rabbit Polyclonal Antibody to MED13
货号: P42133
别名: ARC250; Activator-recruited cofactor 250 kDa component; KIAA0593; T240; THRAP1
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9UHV7
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Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Olsen J.V., Cell 127:635-648(2006).Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).Naeaer A.M., Nature 398:828-832(1999).

Specification

Aliases ARC250; Activator-recruited cofactor 250 kDa component; KIAA0593; T240; THRAP1
Entrez GeneID 9969;
Swissprot Q9UHV7
WB Predicted band size 240kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human MED13.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/50-1/100
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