Rabbit Polyclonal Antibody to PIP5K
货号：
P42147
别名：
1-phosphatidylinositol-4-phosphate 5-kinase; EC 2.7.1.68; FYV1; FYVE finger-containing phosphoinositide kinase; KIAA0981
应用：
WB,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9Y2I7
规格：
目录价
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Description |
|---|
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.Ota T., Nat. Genet. 36:40-45(2004).Sbrissa D., J. Biol. Chem. 277:6073-6079(2002).Brill L.M., Anal. Chem. 76:2763-2772(2004). |
Specification |
|
|---|---|
| Aliases | 1-phosphatidylinositol-4-phosphate 5-kinase; EC 2.7.1.68; FYV1; FYVE finger-containing phosphoinositide kinase; KIAA0981 |
| Entrez GeneID | 200576; |
| Swissprot | Q9Y2I7 |
| WB Predicted band size | 237kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human PIP5K. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IF | 1/100-1/500 |
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