Rabbit Polyclonal Antibody to MRCKB
货号：
P42152
别名：
CDC42-binding protein kinase beta; CDC42BPB; EC 2.7.11.1; MRCK-beta;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y5S2
规格：
目录价
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Description |
|---|
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.Nakajima D., DNA Res. 9:99-106(2002).Olsen J.V., Cell 127:635-648(2006).Hirosawa M., DNA Res. 6:329-336(1999). |
Specification |
|
|---|---|
| Aliases | CDC42-binding protein kinase beta; CDC42BPB; EC 2.7.11.1; MRCK-beta; |
| Entrez GeneID | 9578; |
| Swissprot | Q9Y5S2 |
| WB Predicted band size | 194kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from internal of human MRCKB. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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