Rabbit Polyclonal Antibody to CARD11
货号:
P42172
别名:
Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 3; Carma 1; CARD11; CARMA1
应用:
WB
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q9BXL7
规格:
目录价
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Description |
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Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.Bertin J., J. Biol. Chem. 276:11877-11882(2001).Gaide O., FEBS Lett. 496:121-127(2001).Hillier L.W., Nature 424:157-164(2003). |
Specification |
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Aliases | Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 3; Carma 1; CARD11; CARMA1 |
Entrez GeneID | 84433; |
Swissprot | Q9BXL7 |
WB Predicted band size | 130kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from internal of human CARD11. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |