Rabbit Polyclonal Antibody to CENPA
货号：
P42178
别名：
CENA; CENP-A; Centromere autoantigen A; Centromere protein A;
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P49450
规格：
目录价
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Description |
|---|
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).Sullivan K.F., J. Cell Biol. 127:581-592(1994).Hillier L.W., Nature 434:724-731(2005).Shelby R.D., J. Cell Biol. 136:501-513(1997). |
Specification |
|
|---|---|
| Aliases | CENA; CENP-A; Centromere autoantigen A; Centromere protein A; |
| Entrez GeneID | 1058; |
| Swissprot | P49450 |
| WB Predicted band size | 16kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human CENPA. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| IHC | 1/50-1/100 |
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