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Mouse Monoclonal Antibody to CD196
货号: 31854
别名: CCR6; BN-1; DCR2; DRY6; CCR-6; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6
应用: WB,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P51684
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Description

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

References

1.Cancer Res Treat. 2018 Oct;50(4):1203-1213.
2.Clin Rheumatol. 2017 Jun;36(6):1453-1456.

Specification

Aliases CCR6; BN-1; DCR2; DRY6; CCR-6; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6
Entrez GeneID 1235
Swissprot P51684
clone 7C6D9
WB Predicted band size 42.5kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD196 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200-1/400
ELISA 1/10000
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