Rabbit Polyclonal Antibody to KANK2
货号:
P42277
别名:
Ankyrin repeat domain-containing protein 25; SRC-1-interacting protein; SRC1-interacting protein; Matrix-remodeling-associated protein 3;
应用:
IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q63ZY3
规格:
目录价
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Description |
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Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.Nagase T., DNA Res. 7:143-150(2000).Ota T., Nat. Genet. 36:40-45(2004).Olsen J.V., Cell 127:635-648(2006). |
Specification |
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Aliases | Ankyrin repeat domain-containing protein 25; SRC-1-interacting protein; SRC1-interacting protein; Matrix-remodeling-associated protein 3; |
Entrez GeneID | 25959; |
Swissprot | Q63ZY3 |
WB Predicted band size | 92kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human KANK2. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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IHC | 1/50-1/100 |
IF | 1/100-1/500 |