Rabbit Polyclonal Antibody to BCL2L12
货号：
P42308
别名：
Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9HB09
规格：
目录价
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Description |
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This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983]. |
Specification |
|
|---|---|
| Aliases | Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein; |
| Entrez GeneID | 83596; |
| Swissprot | Q9HB09 |
| WB Predicted band size | 34kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human BCL2L12. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
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