Rabbit Polyclonal Antibody to SLC27A5
货号:
P42319
别名:
EC 6.2.1.7; FACVL3; FATP5; MGC143799; S27A5
应用:
WB,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9Y2P5
规格:
目录价
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Description |
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Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.Steinberg S.J., Mol. Genet. Metab. 68:32-42(1999).Steinberg S.J., J. Biol. Chem. 275:15605-15608(2000).Mihalik S.J., J. Biol. Chem. 277:24771-24779(2002). |
Specification |
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Aliases | EC 6.2.1.7; FACVL3; FATP5; MGC143799; S27A5 |
Entrez GeneID | 10998; |
Swissprot | Q9Y2P5 |
WB Predicted band size | 75kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human SLC27A5. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
IF | 1/100-1/500 |