Rabbit Polyclonal Antibody to DOCK1
货号：
P42383
别名：
180 kDa protein downstream of CRK; dedicator of cytokinesis protein 1; DOC1; DOCK180;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q14185
规格：
目录价
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Description |
|---|
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Hasegawa H., Mol. Cell. Biol. 16:1770-1776(1996).Deloukas P., Nature 429:375-381(2004).Matsuda M., J. Biol. Chem. 271:14468-14472(1996). |
Specification |
|
|---|---|
| Aliases | 180 kDa protein downstream of CRK; dedicator of cytokinesis protein 1; DOC1; DOCK180; |
| Entrez GeneID | 1793; |
| Swissprot | Q14185 |
| WB Predicted band size | 215kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human DOCK1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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