Rabbit Polyclonal Antibody to UBR1
货号：
P42397
别名：
EC 6.3.2.-; Ubiquitin ligase E3 alpha-I;
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q8IWV7
规格：
目录价
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Description |
|---|
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.Kwak K.S., Cancer Res. 64:8193-8198(2004).Dgany O., Am. J. Hum. Genet. 71:1467-1474(2002).Ota T., Nat. Genet. 36:40-45(2004). |
Specification |
|
|---|---|
| Aliases | EC 6.3.2.-; Ubiquitin ligase E3 alpha-I; |
| Entrez GeneID | 197131; |
| Swissprot | Q8IWV7 |
| WB Predicted band size | 36kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human UBR1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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