Rabbit Polyclonal Antibody to RAD18
货号:
P42395
别名:
E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; Postreplication repair protein RAD18
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9NS91
规格:
目录价
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Description |
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E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).Xin H., Nucleic Acids Res. 28:2847-2854(2000).Muzny D.M., Nature 440:1194-1198(2006). |
Specification |
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Aliases | E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; Postreplication repair protein RAD18 |
Entrez GeneID | 56852; |
Swissprot | Q9NS91 |
WB Predicted band size | 56kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human RAD18. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |