Rabbit Polyclonal Antibody to MBTPS1
货号：
P42460
别名：
Endopeptidase S1P; KIAA0091; MBTP1; MBTPS1; membrane-bound transcription factor peptidase
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q14703
规格：
目录价
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Description |
|---|
Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.Nakajima T., J. Hum. Genet. 45:212-217(2000).Nagase T., DNA Res. 2:37-43(1995).Bechtel S., BMC Genomics 8:399-399(2007). |
Specification |
|
|---|---|
| Aliases | Endopeptidase S1P; KIAA0091; MBTP1; MBTPS1; membrane-bound transcription factor peptidase |
| Entrez GeneID | 8720; |
| Swissprot | Q14703 |
| WB Predicted band size | 19kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from C-terminal of human MBTPS1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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