Mouse Monoclonal Antibody to IGF2BP3
货号:
31870
别名:
KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
应用:
WB,IHC,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O00425
规格:
目录价
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Description |
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The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. |
References |
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1.Hum Pathol. 2018 Nov;81:138-147. 2.Cancer Biol Ther. 2018 Jan 2;19(1):42-52. |
Specification |
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Aliases | KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3 |
Entrez GeneID | 10643 |
Swissprot | O00425 |
clone | 1B4D5 |
WB Predicted band size | 63.7kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human IGF2BP3 (AA: 430-579) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200-1/1000 |
FCM | 1/200-1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Flow cytometric analysis of Hela cells using IGF2BP3 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using IGF2BP3 mouse mAb with DAB staining.