Rabbit Polyclonal Antibody to MPRIP
货号：
P42479
别名：
Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; M-RIP; RIP3; p116Rip
应用：
IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q6WCQ1
规格：
目录价
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Description |
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Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. UniProtKB P97434Surks H.K., J. Biol. Chem. 278:51484-51493(2003).Koga Y., J. Biol. Chem. 280:4983-4991(2005).Inazawa J., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases. |
Specification |
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|---|---|
| Aliases | Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; M-RIP; RIP3; p116Rip |
| Entrez GeneID | 23164; |
| Swissprot | Q6WCQ1 |
| WB Predicted band size | 117kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human MPRIP. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| IHC | 1/50-1/100 |
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