Mouse Monoclonal Antibody to MYCN
货号：
31874
别名：
NMYC; ODED; MODED; N-myc; bHLHe37
应用：
IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P04198
规格：
目录价
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Description |
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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
References |
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| 1.Pediatr Blood Cancer. 2018 Oct;65(10):e27257. 2.Proc Natl Acad Sci U S A. 2018 May 8;115(19):4969-4974. |
Specification |
|
|---|---|
| Aliases | NMYC; ODED; MODED; N-myc; bHLHe37 |
| Entrez GeneID | 4613 |
| Swissprot | P04198 |
| clone | 2A4E9 |
| WB Predicted band size | 49.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human MYCN (AA: 337-464) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200-1/1000 |
| FCM | 1/200-1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
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Flow cytometric analysis of Hela cells using MYCN mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using MYCN mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human cerebellum tissues using MYCN mouse mAb with DAB staining.
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