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Rabbit Polyclonal Antibody to NUMA1
货号: P42504
别名: Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen;
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q14980
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Description

Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.Yang C.H., J. Cell Biol. 116:1303-1317(1992).Compton D.A., J. Cell Biol. 116:1395-1408(1992).Maekawa T., J. Cell Sci. 105:589-600(1993).

Specification

Aliases Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen;
Entrez GeneID 4926;
Swissprot Q14980
WB Predicted band size 240kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from internal of human NUMA1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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