Rabbit Polyclonal Antibody to PPP1R16B
货号：
P42533
别名：
TGF-beta-inhibited membrane-associated protein; hTIMAP; CAAX box protein TIMAP; Ankyrin repeat domain-containing protein 4;
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q96T49
规格：
目录价
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Description |
|---|
Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.Cao W., Am. J. Physiol. 283:C327-C337(2002).Nagase T., DNA Res. 5:355-364(1998).Nakajima D., DNA Res. 9:99-106(2002). |
Specification |
|
|---|---|
| Aliases | TGF-beta-inhibited membrane-associated protein; hTIMAP; CAAX box protein TIMAP; Ankyrin repeat domain-containing protein 4; |
| Entrez GeneID | 26051; |
| Swissprot | Q96T49 |
| WB Predicted band size | 64kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human PPP1R16B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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